Article: Impact of stress on memory: adaptation or pathology?

Publié le 05/07/2024

By Marc Dellière

Stressful events are omnipresent in everyday life.

Exposure to these stressors triggers the time-orchestrated release of a multitude of hormones, peptides and neurotransmitters that target brain areas crucial to learning and memory. 

Stress mediators, such as catecholamines and glucocorticoids, affect differently the parts of the brain involved in memory.

Immediately after stress, catecholamines, released by the adrenal medulla and certain cerebral nuclei, disrupt the prefrontal cortex (PFC) but stimulate the amygdala (AMY).

For the hippocampus (HC), they would enhance stress-related memory formation, but could interfere with context processing and memory integration.

Stress affects our memory in several important ways:

1. Memory formation: When we're stressed, our ability to form new memories can be impaired. Stress can make it difficult to concentrate on new information, which can limit our ability to learn effectively.

2. Contextualization of memory: Stress can also influence the way we remember past events in relation to their context. It can make our memories more fragmented, or cause us to focus on certain aspects to the detriment of other important details.

3. Memory retrieval: When we try to remember something under stress, it can be more difficult. Stress can disrupt our ability to retrieve stored information, sometimes making memories less accessible.

4. Memory flexibility: Stress can also affect our ability to adapt our memories to new information or situations. This can make our memories less flexible and more rigid, sometimes preventing us from adjusting them correctly to changing circumstances.

In short, stress not only affects our ability to remember, but also changes the way we process and use our memories.

How Stress Affects Memory: Adaptation and Risk of Pathology

Stress has a significant impact on our memory.

It alters the processes of memory formation, contextualization, retrieval and flexibility, influencing how we react to stressful events.

Short-term adaptation

When we are faced with stress, our bodies release hormones and neurotransmitters that help our brains react quickly and effectively. These substances modify our memory to enable us to focus on the most important aspects of stress and forget less relevant details. This helps us to adapt and deal with new threats more effectively.

Risks of maladaptive behavior

However, these same changes can also have negative effects. If stress is intense or prolonged, it can lead to rigid behaviors, uncontrollable intrusive memories or generalized fear. These effects are often seen in disorders such as anxiety and post-traumatic stress disorder (PTSD).

From Adaptation to Pathology

How stress affects memory depends on many factors, including the specific characteristics of the stress and each person's individual predisposition. Some individuals may cope better with stress thanks to biological differences or previous life experiences.

The importance of individual differences

To effectively treat stress-related mental disorders, it is crucial to take into account individual differences in the way people react to stress. By better understanding these differences, health professionals can develop more personalized and effective treatments.

In short, stress can both help us adapt quickly to new situations and, if mismanaged, contribute to mental disorders.

There are several effective approaches to mitigating the negative effects of stress on memory and mental health. 

Here are some recommended treatments and strategies:

1. Stress Management Techniques: Learning and practicing relaxation techniques such as deep breathing, self-hypnosis, meditation, yoga or visualization can help reduce overall stress levels.

2. Physical exercise: Regular exercise is good for mental health. It reduces stress hormones (such as cortisol) and promotes the release of endorphins, improving mood and resilience to stress.

3. Balanced diet: A healthy, balanced diet can play an important role in stress management. Avoiding excess caffeine, sugar and processed foods can help maintain a stable emotional balance.

4. Quality sleep: Ensuring good sleep is essential for memory consolidation and regulating stress levels. Regular sleep routines and good sleep hygiene can improve the ability to cope with stress.

5. Social Support: Maintaining strong, positive social relationships can provide crucial emotional support in the face of stress. Sharing feelings and receiving support can help reduce the negative effects of stress on mental health.

6. Cognitive-Behavioral Therapy (CBT): CBT is a proven approach to treating anxiety and chronic stress. It helps identify and modify negative thoughts and non-adaptive behaviors related to stress.


In addition, they appear to favorably influence fasting blood glucose, cholesterol and low-density lipoproteins.


Meta-analyses, which are statistical studies combining the results of multiple independent trials on a given subject, indicate that yoga, when asanas are integrated, may have a beneficial effect on stress management by modulating long-term physiological response.

Learn more about Lactium for stress management!

Nos autres actualités